Tripodal Amine Ligands for Accelerating Cu-Catalyzed Azide-Alkyne Cycloaddition: Efficiency and Stability against Oxidation and Dissociation.

@article{Zhu2017TripodalAL,
  title={Tripodal Amine Ligands for Accelerating Cu-Catalyzed Azide-Alkyne Cycloaddition: Efficiency and Stability against Oxidation and Dissociation.},
  author={Zhiling Zhu and Haoqing Chen and Siheng Li and Xunmo Yang and Eric R Bittner and Chengzhi Cai},
  journal={Catalysis science & technology},
  year={2017},
  volume={7 12},
  pages={2474-2485}
}
Ancillary ligands, especially the tripodal ligands such as tris(triazolylmethyl)amines, have been widely used to accelerate the Cu-catalyzed azide-alkyne cycloaddition (CuAAC, a "click" reaction). However, the relationship between the activity of these Cu(I) complexes and their stability against air oxidation and ligand dissociation/exchange was seldom… CONTINUE READING