Triplex-forming DNAs in the human interphase nucleus visualized in situ by polypurine/polypyrimidine DNA probes and antitriplex antibodies

@article{Ohno2002TriplexformingDI,
  title={Triplex-forming DNAs in the human interphase nucleus visualized in situ by polypurine/polypyrimidine DNA probes and antitriplex antibodies},
  author={Mizuki Ohno and Tatsuo Fukagawa and Jeremy S. Lee and Toshimichi Ikemura},
  journal={Chromosoma},
  year={2002},
  volume={111},
  pages={201-213}
}
The polypurine/polypyrimidine (PuPy) tracts present in the human genome are known to be scattered among and within chromosomes. In PuPy tract sequences, triplex formation occurs readily under physiological conditions, leaving single-stranded DNAs capable of hybridization with complementary single-stranded DNAs and RNAs. The formation of single-strands and transmolecular triplexes is thought to enable sequences spaced distantly along the genome to associate with each other and organize nuclear… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Distribution of polypurine / polypyrimidine tract sequences in the human MHC regions and their possible functions

S Kanaya, T Fukagawa, +3 authors T Ikemura
Major histocompatibility complex : evolution , structure , and function • 2000

Non - B DNA structures spatially and sequence - specifically associated with individual centromeres in the human interphase nucleus

M Ohno, T Tenzen, +3 authors T Ikemura
Chromosomes Today • 2000

nome and subnuclear organization of non - B forming DNA structures in mammalian chromosomes

T Ikemura, M Ohno, T Uemura, H Sasaki, T Tenzen
Cytogenet Cell Genet • 1998

Similar Papers

Loading similar papers…