Triple marker screening for trisomy 21, trisomy 18 and open neural tube defects in singleton pregnancies of native Japanese pregnant women.

@article{Onda2000TripleMS,
  title={Triple marker screening for trisomy 21, trisomy 18 and open neural tube defects in singleton pregnancies of native Japanese pregnant women.},
  author={Takashi Onda and Teruaki Tanaka and Katsuaki Yoshida and Yoshio Nakamura and Riko Kudo and Haruyoshi Yamamoto and Akio Sato and Kaoru Yanagida and Yoshihiro Takai and Hirokazu Uemura and Keika Hoshi and Yuko Fukada and Yoshihiro Miyake and Masatoshi Ohnishi and Tsuyoshi Kaneoka and Yasuo Makino and Yokob Murata and Toru Kanzaki and Haruhide Kanzaki and Takanobu Osaki and Toyokazu Aono and Kazuo Maeda and Sachio Ogita and Seiichi Yamamasu and Tomoyoshi Aso and Yukiko Shimizu and Toshihiko Izutsu and Tohru Kudo and Takashi Okai and Miki Sakai and Tetsuaki Hashimoto and Nobuo Matsuzaki and Masatoshi Kitagawa and Haruhiko Sago and Robert E. Grier and Florence Myrick},
  journal={The journal of obstetrics and gynaecology research},
  year={2000},
  volume={26 6},
  pages={
          441-7
        }
}
OBJECTIVE To report the results of prenatal triple marker screening on a population of Japanese pregnant women. METHODS From April 1994 through March 1999, a total of 32,925 native Japanese women with singleton pregnancies requested a triple marker-screening test. Multiples of the median values for 3 markers and individual risks for each patient were calculated following adjustment for the Japanese weight correction factor. The risk cut-off values used for Down syndrome (T21), open spina… CONTINUE READING
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