Triple marker screening for trisomy 21, trisomy 18 and open neural tube defects in singleton pregnancies of native Japanese pregnant women.

@article{Onda2000TripleMS,
  title={Triple marker screening for trisomy 21, trisomy 18 and open neural tube defects in singleton pregnancies of native Japanese pregnant women.},
  author={Takashi Onda and Toshitaka Tanaka and Kana Yoshida and Yoshiko Nakamura and Ryuichi Kudo and Haruko Yamamoto and Akira Sato and Kaoru Yanagida and Yasushi Takai and Hirokazu Uemura and Kazuhiko Hoshi and Yukihito Fukada and Yoshihiro Miyake and Masayoshi Ohnishi and Tsuyoshi Kaneoka and Yasuo Makino and Yuji Murata and Toru Kanzaki and Haruhide Kanzaki and Takanobu Osaki and Toshihiro Aono and Kazuo Maeda and Sachio Ogita and Seiichi Yamamasu and Takeshi Aso and Toshihiko Izutsu and Tooru Kudo and Takashi Okai and Masatoshi Sakai and Toshihiro Hashimoto and Naoyuki Matsuzaki and Michihiko Kitagawa and Haruhiko Sago and Robert E Grier and Florence T Myrick and Yukiko Shimizu},
  journal={The journal of obstetrics and gynaecology research},
  year={2000},
  volume={26 6},
  pages={441-7}
}
OBJECTIVE To report the results of prenatal triple marker screening on a population of Japanese pregnant women. METHODS From April 1994 through March 1999, a total of 32,925 native Japanese women with singleton pregnancies requested a triple marker-screening test. Multiples of the median values for 3 markers and individual risks for each patient were calculated following adjustment for the Japanese weight correction factor. The risk cut-off values used for Down syndrome (T21), open spina… CONTINUE READING