Triple-layered PLGA/nanoapatite/lauric acid graded composite membrane for periodontal guided bone regeneration.

@article{JamunaThevi2014TriplelayeredPA,
  title={Triple-layered PLGA/nanoapatite/lauric acid graded composite membrane for periodontal guided bone regeneration.},
  author={Kalitheertha Jamuna-Thevi and Nur Najiha Saarani and Mohamed Rafiq Abdul Kadir and Hendra Hermawan},
  journal={Materials science & engineering. C, Materials for biological applications},
  year={2014},
  volume={43},
  pages={253-63}
}
This paper discusses the successful fabrication of a novel triple-layered poly(lactic-co-glycolic acid) (PLGA)-based composite membrane using only a single step that combines the techniques of solvent casting and thermally induced phase separation/solvent leaching. The resulting graded membrane consists of a small pore size layer-1 containing 10 wt% non-stoichiometric nanoapatite (NAp)+1-3 wt% lauric acid (LA) for fibroblastic cell and bacterial inhibition, an intermediate layer-2 with 20-50 wt… CONTINUE READING

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