Triple-color coincidence analysis: one step further in following higher order molecular complex formation.

@article{Heinze2004TriplecolorCA,
  title={Triple-color coincidence analysis: one step further in following higher order molecular complex formation.},
  author={K. Heinze and M. Jahnz and P. Schwille},
  journal={Biophysical journal},
  year={2004},
  volume={86 1 Pt 1},
  pages={
          506-16
        }
}
Confocal fluorescence spectroscopy is a versatile method for studying dynamics and interactions of biomolecules in their native environment with minimal interference with the observed system. Analyzing coincident fluctuations induced by single molecule movement in spectrally distinct detection channels, dual-color fluorescence cross-correlation, and coincidence analysis have proven most powerful for probing the formation or cleavage of molecular bonds in real time. The similarity of the optical… Expand
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