Triphenyltetrazolium and its derivatives are anisotropic inhibitors of energy transduction in oxidative phosphorylation in rat liver mitochondria.

@article{Higuti1983TriphenyltetrazoliumAI,
  title={Triphenyltetrazolium and its derivatives are anisotropic inhibitors of energy transduction in oxidative phosphorylation in rat liver mitochondria.},
  author={Tomihiko Higuti and R P Arakaki and Y Kotera and Masaharu Takigawa and Ikuko Tani and Masaaki Shibuya},
  journal={Biochimica et biophysica acta},
  year={1983},
  volume={725 1},
  pages={1-9}
}
Triphenyltetrazolium and its derivatives inhibited energy transduction in mitochondria but not in submitochondrial particles, which are inside-out relative to the membranes of mitochondria. Triphenyltetrazolium incorporated into the inside of submitochondrial particles inhibited ATP synthesis in the particles. Triphenyltetrazolium also inhibited the… CONTINUE READING