Triphenyl phosphite neuropathy differs from organophosphorus-induced delayed neuropathy in rats.

@article{Veronesi1987TriphenylPN,
  title={Triphenyl phosphite neuropathy differs from organophosphorus-induced delayed neuropathy in rats.},
  author={Bellina Veronesi and C L Dvergsten},
  journal={Neuropathology and applied neurobiology},
  year={1987},
  volume={13 3},
  pages={193-208}
}
The topographies of neuropathic damage produced by triphenyl phosphite (TPP) and tri-ortho-cresyl phosphate (TOCP) are contrasted in the present study. Long-Evans, male rats were exposed (sc) to single (0.1 ml kg-1; 1.0 ml kg-1) or multiple (2 X 1.0 ml kg-1; 3 X 1.0 ml kg-1) doses of TPP, and sampled 1-3 weeks after exposure. Additional animals were dosed acutely with TOCP (1160 mg kg-1, p.o.) alone or in combination with multiple doses of TPP (2 X 1 ml kg-1). Functional changes, seen in… CONTINUE READING

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