Tripartite synapses: astrocytes process and control synaptic information

  title={Tripartite synapses: astrocytes process and control synaptic information},
  author={G. Perea and M. Navarrete and A. Araque},
  journal={Trends in Neurosciences},
  • G. Perea, M. Navarrete, A. Araque
  • Published 2009
  • Biology, Medicine
  • Trends in Neurosciences
  • The term 'tripartite synapse' refers to a concept in synaptic physiology based on the demonstration of the existence of bidirectional communication between astrocytes and neurons. Consistent with this concept, in addition to the classic 'bipartite' information flow between the pre- and postsynaptic neurons, astrocytes exchange information with the synaptic neuronal elements, responding to synaptic activity and, in turn, regulating synaptic transmission. Because recent evidence has demonstrated… CONTINUE READING
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