Trimipramine: Pharmacological reevaluation and comparison with clozapine

@article{Gross1991TrimipraminePR,
  title={Trimipramine: Pharmacological reevaluation and comparison with clozapine},
  author={Gerhard Gross and Xin Xie and Markus Gastpar},
  journal={Neuropharmacology},
  year={1991},
  volume={30},
  pages={1159-1166}
}
Trimipramine has been reported to differ from other typical tricyclic antidepressant drugs in several aspects, for instance it does not inhibit neuronal transmitter uptake and does not cause down-regulation of beta-adrenoceptors. Moreover, it may possess antipsychotic activity in schizophrenic patients. In the present investigation it was found that trimipramine did not alter the electrically-induced release of [3H]noradrenaline and [3H]5-hydroxytryptamine, from slices of the cerebral cortex of… 
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