Trimethylation of histone H3 lysine 4 is an epigenetic mark at regions escaping mammalian X inactivation.

Abstract

It is now estimated that 150-200 genes clustered in several discrete regions escape X inactivation in somatic cells of human females by unknown mechanisms. Here, we show that although the human female inactive X chromosome is largely devoid of histone 3 lysine 4 trimethylation (H3K4me3), regions that are known to escape X inactivation, including the… (More)

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@article{Khalil2007TrimethylationOH, title={Trimethylation of histone H3 lysine 4 is an epigenetic mark at regions escaping mammalian X inactivation.}, author={Ahmad M. Khalil and Daniel J. Driscoll}, journal={Epigenetics}, year={2007}, volume={2 2}, pages={114-8} }