Trimethoprim/sulfonamide combinations in the horse: a review.

  title={Trimethoprim/sulfonamide combinations in the horse: a review.},
  author={Engeline van Duijkeren and Arnold Vulto and A S J P A M van Miert},
  journal={Journal of veterinary pharmacology and therapeutics},
  volume={17 1},
The indications for use, side-effects, and pharmacokinetic parameters of trimethoprim, sulfonamides and their combinations in the horse are reviewed. Trimethoprim/sulfonamide (TMPS) combinations are used for the treatment of various diseases caused by gram-positive and gram-negative bacteria, including infections of the respiratory tract, urogenital tract, alimentary tract, skin joints and wounds. TMPS combinations can be administered orally, since absorption from the gastrointestinal tract is… CONTINUE READING