Trimeric hemibastadin congener from the marine sponge Ianthella basta.

@article{Niemann2013TrimericHC,
  title={Trimeric hemibastadin congener from the marine sponge Ianthella basta.},
  author={Hendrik Niemann and Wenhan Lin and Werner E. G. M{\"u}ller and Michael Kubbutat and Daowan Lai and Peter Proksch},
  journal={Journal of natural products},
  year={2013},
  volume={76 1},
  pages={
          121-5
        }
}
The first naturally occurring trimeric hemibastadin congener, sesquibastadin 1 (1), and the previously reported bastadins 3, 6, 7, 11, and 16 (2-6) were isolated from the marine sponge Ianthella basta, collected in Indonesia. The structure of 1 was elucidated on the basis of 1D and 2D NMR measurements and by HRMS. Among all the isolated compounds, the linear sesquibastadin 1 (1) and bastadin 3 (2) showed the strongest inhibition rates for at least 22 protein kinases (IC(50) = 0.1-6.5 μM), while… 
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