Trilostane in the Treatment of Primary Adrenocortical Micronodular Dysplasia (pamd)

@article{Krabbe1986TrilostaneIT,
  title={Trilostane in the Treatment of Primary Adrenocortical Micronodular Dysplasia (pamd)},
  author={S\oren Krabbe and M Damkjaer},
  journal={Pediatric Research},
  year={1986},
  volume={20},
  pages={1203-1203}
}
A rare cause of Cushing's syndrome is a pituitary-independant nodular dysplasia of the adrenal cortex. A 4 year old girl presented with advanced clinical features of Cushing's syndrome. Abdominal CT-scan and adrenal scintigraphy revealed bilateral adrenal hyperplasia whereas a cerebral CT-scan was normal. Serial determinations of plasma ACTH together with dynamic tests using dexamethasone, metyrapone and vasopressin indicated a primary, autonomous, adrenal dysfunction. Treatment with Trilostane… CONTINUE READING