Triiodothyronine reverses depressed contractile performance after excessive catecholamine stimulation.

@article{Timek1998TriiodothyronineRD,
  title={Triiodothyronine reverses depressed contractile performance after excessive catecholamine stimulation.},
  author={T. Timek and C. Vahl and A. Bonz and L. Sch{\"a}ffer and M. Rosenberg and S. Hagl},
  journal={The Annals of thoracic surgery},
  year={1998},
  volume={66 5},
  pages={
          1618-25
        }
}
  • T. Timek, C. Vahl, +3 authors S. Hagl
  • Published 1998
  • Medicine
  • The Annals of thoracic surgery
  • BACKGROUND Conflicting results have been reported regarding the acute effects of triiodothyronine (T3) on myocardial contractile performance. The present study analyzes the role of T3 in reversing the depressant effect of excessive catecholamine stimulation in isolated porcine left ventricular myocardium. METHODS Thirty-six left ventricular trabeculae (0.4 x 6.0 mm) obtained from 6 pigs were used for measurements of isometric force development, isotonic shortening, and intracellular calcium… CONTINUE READING
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