Triiodothyronine reverses depressed contractile performance after excessive catecholamine stimulation.
@article{Timek1998TriiodothyronineRD, title={Triiodothyronine reverses depressed contractile performance after excessive catecholamine stimulation.}, author={T. Timek and C. Vahl and A. Bonz and L. Sch{\"a}ffer and M. Rosenberg and S. Hagl}, journal={The Annals of thoracic surgery}, year={1998}, volume={66 5}, pages={ 1618-25 } }
BACKGROUND
Conflicting results have been reported regarding the acute effects of triiodothyronine (T3) on myocardial contractile performance. The present study analyzes the role of T3 in reversing the depressant effect of excessive catecholamine stimulation in isolated porcine left ventricular myocardium.
METHODS
Thirty-six left ventricular trabeculae (0.4 x 6.0 mm) obtained from 6 pigs were used for measurements of isometric force development, isotonic shortening, and intracellular calcium… CONTINUE READING
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References
SHOWING 1-10 OF 39 REFERENCES
Facilitated recovery of cardiac performance by triiodothyronine following a transient ischemic insult.
- Medicine
- Cardiology
- 1992
- 14
Acute Increase in Cardiac Performance After Triiodothyronine: Blunted Response in Amiodarone‐Treated Pigs
- Medicine
- Journal of cardiovascular pharmacology
- 1994
- 14
L-triiodothyronine acutely increases Ca2+ uptake in the isolated, perfused rat heart. Changes in L-type Ca2+ channels and beta-receptors during short- and long-term hyper- and hypothyroidism.
- Medicine
- European journal of endocrinology
- 1994
- 26
Intracellular calcium transient of working human myocardium of seven patients transplanted for congestive heart failure.
- Chemistry, Medicine
- Circulation research
- 1994
- 81
- PDF
Enhanced phosphorylation of myocardial sarcoplasmic reticulum in experimental hyperthyroidism.
- Biology, Medicine
- The American journal of physiology
- 1978
- 36
Rabbit myocardial membrane Ca2+-adenosine triphosphatase activity: stimulation in vitro by thyroid hormone.
- Biology, Medicine
- Archives of biochemistry and biophysics
- 1984
- 72
Cyclic adenosine monophosphate effects on the myocardium: a man who blows hot and cold with one breath.
- Medicine
- Journal of the American College of Cardiology
- 1983
- 124
- PDF
Phosphorylation and Adenosine Triphosphatase Activity of Myofibrils from Thyrotoxic Rabbit Hearts
- Chemistry, Medicine
- Circulation research
- 1981
- 32
- PDF
The novel effects of 3,5,3'-triiodo-L-thyronine on myocyte contractile function and beta-adrenergic responsiveness in dilated cardiomyopathy.
- Medicine
- The Journal of thoracic and cardiovascular surgery
- 1994
- 52