Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity.

@article{Avner1987TriiodothyronineinducedCF,
  title={Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity.},
  author={Ellis D. Avner and William E. Sweeney and Nicholas P. Piesco and Demetrius E Ellis},
  journal={The Journal of laboratory and clinical medicine},
  year={1987},
  volume={109 4},
  pages={441-53}
}
Previous organ culture investigations into the pathogenesis of renal cyst formation have demonstrated that glucocorticoid-induced proximal tubular cyst formation is associated with increases in renal sodium-potassium adenosine triphosphatase (Na-K-ATPase) activity. To explore the relationship between cyst production and transport enzyme induction, we examined the effects of the potent inducer of Na-K-ATPase activity, L-3,5,3'-triiodothyronine (T3), on renal tubular morphologic and enzymatic… CONTINUE READING

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