Triidothyronine-induced reversal of learned helplessness in rats

@article{Martin1985TriidothyronineinducedRO,
  title={Triidothyronine-induced reversal of learned helplessness in rats},
  author={P. Martin and Denis Brochet and Philippe Soubrié and Pierre Simon},
  journal={Biological Psychiatry},
  year={1985},
  volume={20},
  pages={1023-1025}
}

Strong interactions between learned helplessness and risky decision-making in a rat gambling model

Results suggest that while baseline risky decision making may not predict LH behaviour it interacts strongly with LH conditions in modulating subsequent decision-making behaviour, and the suggested possibility that stress controllability may be a key factor should be further investigated.

Active behavioral coping alters the behavioral but not the endocrine response to stress

Effect of Triiodothyronine on Antidepressant Screening Tests in Mice and on Presynaptic 5-HT1A Receptors: Mediation by Thyroid Hormone α Receptors

Blockade by dronedarone of the antidepressant-like effects of T3 suggests that these effects are TRα receptor-mediated, and suggests a possible gender disparity in the role of presynaptic 5-HT1A receptors in T3 antidepressant mechanisms.

Thyrotropin-releasing hormone receptor 1-deficient mice display increased depression and anxiety-like behavior.

These results provide the first direct evidence that the endogenous TRH system is involved in mood regulation, and this function is carried out through TRH-R1-mediated neural pathways.

Antidepressant-like effects of triiodothyroacetic acid in mice

TA3 was effective on the same psychopharmacological tests which have previously been used to demonstrate the antidepressant-like effects of T3, and might, therefore, be preferable to T3 for clinical use in depression.

Thyroid Hormones in Depressive Disorders: A Reappraisal of Clinical Utility

Research findings include an association of subclinical hypothyroidism with unsatisfactory responses to antidepressant treatment, evidence that triiodothyronine and thyroid‐stimulating hormone may speed recovery in acute depression, and limited and inconsistent support for the effectiveness of exogenous thyroid hormones to augment antidepressants.

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Learned helplessness decreases [3H]imipramine binding in rat cortex.

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