Trigoxyphins A-G: diterpenes from Trigonostemon xyphophylloides.

  title={Trigoxyphins A-G: diterpenes from Trigonostemon xyphophylloides.},
  author={Bing-Dong Lin and Mei-Ling Han and Yin-chun Ji and Hua-dong Chen and Sheng-ping Yang and Sheng Zhang and Mei-yu Geng and Jian-Min Yue},
  journal={Journal of natural products},
  volume={73 7},
Six new oxygenated daphnane-type diterpenoids, trigoxyphins A-F (1-6), a phenanthrene-type diterpenoid, trigoxyphin G (7), and two known compounds were isolated from twigs of Trigonostemon xyphophylloides. Their structures were established using spectroscopic methods. Compounds 1 and 2 exhibited strong cytotoxic activity against HL60 (IC(50): 0.27 and 0.49 microM) and A549 (IC(50): 7.5 and 4.9 microM) tumor cell lines, respectively.