Highly Influenced
Trigoxyphins A-G: diterpenes from Trigonostemon xyphophylloides.
@article{Lin2010TrigoxyphinsAD, title={Trigoxyphins A-G: diterpenes from Trigonostemon xyphophylloides.}, author={Bing-Dong Lin and Mei-Ling Han and Yin-chun Ji and Hua-dong Chen and Sheng-ping Yang and Sheng Zhang and Mei-yu Geng and Jian-Min Yue}, journal={Journal of natural products}, year={2010}, volume={73 7}, pages={ 1301-5 } }
- Published in Journal of natural products 2010
DOI:10.1021/np100320h
Six new oxygenated daphnane-type diterpenoids, trigoxyphins A-F (1-6), a phenanthrene-type diterpenoid, trigoxyphin G (7), and two known compounds were isolated from twigs of Trigonostemon xyphophylloides. Their structures were established using spectroscopic methods. Compounds 1 and 2 exhibited strong cytotoxic activity against HL60 (IC(50): 0.27 and 0.49 microM) and A549 (IC(50): 7.5 and 4.9 microM) tumor cell lines, respectively.