Triggers and tricks of Plasmodium sexual development.

@article{Kooij2007TriggersAT,
  title={Triggers and tricks of Plasmodium sexual development.},
  author={Taco W. A. Kooij and Kai Matuschewski},
  journal={Current opinion in microbiology},
  year={2007},
  volume={10 6},
  pages={547-53}
}
Irrespective of the tremendous suffering caused by malaria, a Plasmodium infection by pathogenic blood stages is only transient and an obligate step toward the Anopheles vector where sexual reproduction and genetic recombination of the unicellular parasite takes place. Recent expression profiling studies identified the molecular make-up of female and male gametocytes. Differential promoters and translational repression through mRNA binding by a female-specific helicase help to fine-tune the… CONTINUE READING