Triggers and Anatomical Substrates in the Genesis and Perpetuation of Atrial Fibrillation

  title={Triggers and Anatomical Substrates in the Genesis and Perpetuation of Atrial Fibrillation},
  author={Damian S{\'a}nchez-Quintana and Jos{\'e} Ram{\'o}n L{\'o}pez-M{\'i}nguez and Gonzalo E. Pizarro and Margarita Murillo and Jos{\'e} {\'A}ngel Cabrera},
  booktitle={Current cardiology reviews},
The definition of atrial fibrillation (AF) as a functional electrical disorder does not reflect the significant underlying structural abnormalities. Atrial and Pulmonary Vein (PV) muscle sleeve microstructural remodeling is present, and establishes a vulnerable substrate for AF maintenance. In spite of an incomplete understanding of the anatomo-functional basis for AF, current evidence demonstrates that this arrhythmia usually requires a trigger for initiation and a vulnerable… CONTINUE READING

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Alteraciones estructurales precoces asociadas al remodelado eléctrico de la fibrilación auricular en un modelo canino de estimulación auricular sostenida a altas frecuencias

  • JA Cabrera, V Climent, M Murillo
  • Efecto protector del Irbesartán. Revista…
  • 2010
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