Triggering receptor expressed on myeloid cells-1 and 2 in bronchoalveolar lavage fluid in pulmonary sarcoidosis.

@article{Suchankova2013TriggeringRE,
  title={Triggering receptor expressed on myeloid cells-1 and 2 in bronchoalveolar lavage fluid in pulmonary sarcoidosis.},
  author={Magda Suchankova and M{\'a}ria Bucov{\'a} and Elena Tibenska and Eva Tedlov{\'a} and Juraj Demian and Ivan Majer and Helena Novosadova and Miroslav Tedla and Ema Paulovi{\vc}ov{\'a} and Daniela Kant{\'a}rov{\'a}},
  journal={Respirology},
  year={2013},
  volume={18 3},
  pages={455-62}
}
BACKGROUND AND OBJECTIVE Pulmonary sarcoidosis (PS) is characterized by the formation of granulomas in the lungs and has been associated with infection by microorganisms. Triggering receptor expressed on the surface of myeloid cells (TREM)-1 is overexpressed in response to infection while TREM-2 is involved in granuloma formation. We hypothesized that these receptors are overexpressed in PS and might be useful for diagnostic testing. METHODS Cell surface TREM-1 and TREM-2 expression in cells… CONTINUE READING