Triggered firing in pulmonary veins initiated by in vitro autonomic nerve stimulation.

  title={Triggered firing in pulmonary veins initiated by in vitro autonomic nerve stimulation.},
  author={Eugene Patterson and Sunny S. Po and Benjamin J. Scherlag and Ralph Lazzara},
  journal={Heart rhythm},
  volume={2 6},
BACKGROUND Rapid firing within pulmonary vein sleeves frequently initiates atrial fibrillation. The role of the autonomic nervous system in facilitating spontaneous firing is unknown. OBJECTIVES The purpose of this study was to determine if autonomic nerve stimulation within canine atrium and pulmonary vein sleeves initiates arrhythmia formation. METHODS Extracellular bipolar and intracellular microelectrode recordings were obtained from isolated superfused canine pulmonary veins (N = 28… CONTINUE READING
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