Trigeminal neuralgia

@article{Zakrzewska2014TrigeminalN,
  title={Trigeminal neuralgia},
  author={Joanna M. Zakrzewska and Mark E. Linskey},
  journal={BMJ : British Medical Journal},
  year={2014},
  volume={348}
}
Trigeminal neuralgia is a rare, episodic facial pain that is unilateral, electric shock-like, and provoked by light touch. At first, it is often mistaken as a tooth problem owing to its presentation in the two lower branches of the trigeminal nerve. Patients may undergo unnecessary—and sometimes irreversible—dental treatment before the condition is recognised. Initially, a small dose of an antiepileptic drug (such as carbamazepine) rather than any analgesic drug can provide excellent pain… 
A Comprehensive Review of Trigeminal Neuralgia
TLDR
Deep brain and motor cortex neuro-modulatory stimulation are off label emerging techniques which may offer relief to TN that is otherwise refractory to pharmacological management and surgery.
Recurrent Trigeminal Neuralgia: A Case Series and a Review of the Literature
TLDR
This report presents a series of two cases of recurrent trigeminal neuralgia, a peripheral neuropathy characterized by intermittent episodes of severe facial pain originating in the sensory nucleus of the trigemINAL nerve, which is primarily managed medically, although many patients may require surgical or radiotherapeutic intervention.
Trigeminal Neuralgia: Current Approaches and Emerging Interventions
TLDR
Fundamentally, TN remains a clinical diagnosis that must be distinguished from other types of trigeminal neuropathic pain and/or facial pain associated with other neuralgias or headache syndromes, and elucidation of the molecular mechanisms underlying trigeminals neuralgia will pave the way for novel, more effective and less invasive therapies.
Trigeminal Neuralgia: Etiology, Diagnosis, and Treatment
TLDR
The objective of this article is to summarize the current literature surrounding the classification, epidemiology, presentation, and pathophysiology of TN while also including the current and evidence-based knowledge on the diagnosis and treatment options.
Carcinoma of the Tongue Presenting as Trigeminal Neuralgia: A Case Report
TLDR
The case of an 81-year-old woman diagnosed with invasive oral squamous cell carcinoma presenting as trigeminal neuralgia is discussed, with a view to developing a treatment plan prior to any intervention.
Temporomandibular disorder and other causes of orofacial pain: first international classification and new treatment perspectives
TLDR
The aim of this paper is to review the new International classification of orofacial pain as well as the prevalence, pathophysiology and treatment of the temporomandibular disorder, trigeminal neuralgia, persistent idiopathic facial pain, burning mouth syndrome and other forms of Orof facial pain.
Greater palatine block for V2 trigeminal neuralgia: Case report
TLDR
A novel nerve block directed at the maxillary (V2) division of the fifth cranial nerve is described as treatment for medication-refractory trigeminal neuralgia (TN) and is a diagnostic feature for the dentist to differentiate between sources of facial pain.
Structural Abnormalities and Treatment-related Plasticity in Classical Trigeminal Neuralgia
TLDR
To determine if there are structural neural abnormalities in patients with TN and whether effective neurosurgical treatment can reverse these abnormalities, a large number of patients were diagnosed with classical trigeminal neuralgia.
Subtle Sensory Abnormalities Detected by Quantitative Sensory Testing in Patients with Trigeminal Neuralgia.
TLDR
QST shows subtle sensory abnormalities in patients with TN despite not being detected in routine clinical examination and may provide a basis for further research on the development of TN and also on improvement after treatment.
Therapeutic Outcome and Future Scopes in the Management of Trigeminal Neuralgia
TLDR
Microvascular decompression is performed to address the primary problem of aberrant vascular loops impinging on the trigeminal nerve and percutaneous destructive procedures aim at reducing the overall sensory input from the trigEMinal ganglion.
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TLDR
Clinical manifestations are the mainstay for diagnosis because there are no objective tests to validate the diagnosis of trigeminal neuralgia and the sensitivity and specificity of these clinical manifestations is reviewed.
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TLDR
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TLDR
Carbamazepine or oxcarbazepine should be offered as first‐line treatment for pain control and microvascular decompression may be considered over other surgical techniques to provide the longest duration of pain freedom in patients with TN.
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TLDR
Routine head imaging identifies structural causes in up to 15% of patients and may be considered useful in distinguishing STN from classic trigeminal neuralgia and the role of surgery vs pharmacotherapy in the management of TN in patients with MS remains uncertain.
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
High-quality prospective studies of MVD in a population that has been well phenotyped and which is assessed pre and postoperatively using psychometrically tested questions, administered at regular intervals by independent observers, are needed to provide clear evidence of its superiority over medical therapies.
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