Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics.

@article{Bayston2007TriclosanRI,
  title={Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics.},
  author={Roger R Bayston and Waheed Ashraf and Toni Smith},
  journal={The Journal of antimicrobial chemotherapy},
  year={2007},
  volume={59 5},
  pages={848-53}
}
OBJECTIVES Triclosan is in widespread use in domestic, commercial and healthcare settings and is used to reduce methicillin-resistant Staphylococcus aureus (MRSA) load in carriers. Triclosan resistance is uncommon, usually being due to mutation in fabI or overexpression of efflux pumps. This study investigated the ability of triclosan-containing silicone elastomer to kill MRSA adherent to its surface. METHODS Silicone discs containing triclosan were prepared by a matrix-expansion method… CONTINUE READING
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Patent: Medical devices and methods of making medical devices

  • R. Bayston
  • University of Nottingham. WO06032904,
  • 2005
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