Triclosan: environmental exposure, toxicity and mechanisms of action

@article{Dann2011TriclosanEE,
  title={Triclosan: environmental exposure, toxicity and mechanisms of action},
  author={A. Dann and A. Hontela},
  journal={Journal of Applied Toxicology},
  year={2011},
  volume={31}
}
Triclosan [5‐chloro‐2‐(2,4‐dichlorophenoxy)phenol; TCS] is a broad spectrum antibacterial agent used in personal care, veterinary, industrial and household products. TCS is commonly detected in aquatic ecosystems, as it is only partially removed during the wastewater treatment process. Sorption, biodegradation and photolytic degradation mitigate the availability of TCS to aquatic biota; however the by‐products such as methyltriclosan and other chlorinated phenols may be more resistant to… Expand
Occurrence and toxicity of antimicrobial triclosan and by-products in the environment
TLDR
The excessive use of triclosan is suspected to increase the risk of emergence of TCS-resistant bacteria and the selection of resistant strains, as well as to produce cytotoxic, genot toxic, and endocrine disruptor effects. Expand
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TLDR
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The synthetic biocides triclosan and triclocarban are routinely added to a wide array of antimicrobial personal care products and consumer articles and exhibit toxicity toward a number of biological receptors. Expand
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TLDR
Triclosan exerts a marked influence on algae, which are important organisms being the first-step producers in the ecosystem; therefore, the possible destruction of the balance of the ecosystem is expected if triclosan is discharged into the environment at high levels. Expand
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TLDR
The neutral form of TCS, a chlorinated biphenyl ether used as an antimicrobial in consumer products, was determined to be associated with toxic effects and Ionization and sorption will mitigate those effects in the aquatic compartment. Expand
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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