Triclosan: a critical review of the experimental data and development of margins of safety for consumer products.

  title={Triclosan: a critical review of the experimental data and development of margins of safety for consumer products.},
  author={Joseph V. Rodricks and James A. Swenberg and Joseph Francis Borzelleca and Robert R. Maronpot and Annette M. Shipp},
  journal={Critical reviews in toxicology},
  volume={40 5},
Triclosan (2,4,4'-trichloro-2'-hydroxy-diphenyl ether) is an antibacterial compound that has been used in consumer products for about 40 years. The tolerability and safety of triclosan has been evaluated in human volunteers with little indication of toxicity or sensitization. Although information in humans from chronic usage of personal care products is not available, triclosan has been extensively studied in laboratory animals. When evaluated in chronic oncogenicity studies in mice, rats, and… CONTINUE READING
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