Trick or treat from food endocannabinoids?

@article{Marzo1998TrickOT,
  title={Trick or treat from food endocannabinoids?},
  author={Vincenzo Di Marzo and Nunzio Sepe and Luciano Petrocellis and Alvin Berger and Gayle Crozier and Ester Fride and Raphael Mechoulam},
  journal={Nature},
  year={1998},
  volume={396},
  pages={636-636}
}
The discovery of the endogenous cannabinoid N-arachidonoylethanolamine (anandamide) and other N-acylethanolamines (NAEs) in chocolate has led to speculation that the purported rewarding properties of cocoa are due to the presence of compounds “that could act as cannabinoid mimics”. This observation raises some important questions. First, are NAEs and anandamide, or the ‘endocannabinoid’ 2-arachidonoylglycerol (2-AG), present in widely consumed foods (such as milk) that are less ‘rewarding’ than… 
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The role of the endocannabinoid system in appetite stimulation in the adult organism, and perhaps more importantly, its critical involvement in milk ingestion and survival of the newborn, may not only further the understanding of the physiology of food intake and growth, but may also find therapeutic applications in wasting disease and infant's "failure to thrive".
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