Trichostatin A Selectively Suppresses the Cold-Induced Transcription of the ZmDREB1 Gene in Maize

@inproceedings{Hu2011TrichostatinAS,
  title={Trichostatin A Selectively Suppresses the Cold-Induced Transcription of the ZmDREB1 Gene in Maize},
  author={Yong Hu and Lu Zhang and Lin Zhao and Jun Li and Shibin He and Kun Zhou and Fei Yang and Min Huang and Li Jiang and Lijia Li},
  booktitle={PloS one},
  year={2011}
}
Post-translational modifications of histone proteins play a crucial role in responding to environmental stresses. Histone deacetylases (HDACs) catalyze the removal of an acetyl group from histones and are generally believed to be a transcriptional repressor. In this paper, we report that cold treatment highly induces the up-regulation of HDACs, leading to global deacetylation of histones H3 and H4. Treatment of maize with the HDAC inhibitor trichostatin A (TSA) under cold stress conditions… CONTINUE READING