Trichosetin, a Novel Tetramic Acid Antibiotic Produced in Dual Culture of Trichoderma harzianum and Catharanthus roseus Callus

@article{Marfori2002TrichosetinAN,
  title={Trichosetin, a Novel Tetramic Acid Antibiotic Produced in Dual Culture of Trichoderma harzianum and Catharanthus roseus Callus},
  author={E. C. Marfori and S. Kajiyama and E. Fukusaki and A. Kobayashi},
  journal={Zeitschrift f{\"u}r Naturforschung C},
  year={2002},
  volume={57},
  pages={465 - 470}
}
  • E. C. Marfori, S. Kajiyama, +1 author A. Kobayashi
  • Published 2002
  • Biology, Medicine
  • Zeitschrift für Naturforschung C
  • The dual culture of Trichoderma harzianum and Catharanthus roseus callus produced an antimicrobial compound with a remarkable activity against the Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis. Structural elucidation revealed that this compound, which we have named trichosetin, is a novel tetramic acid (2,4-pyrrolidinedione) antibiotic and a homolog of the fungal metabolite equisetin. This compound however, was not produced in the individual culture of T. harzianum or C… CONTINUE READING
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