Trichosetin, a Novel Tetramic Acid Antibiotic Produced in Dual Culture of Trichoderma harzianum and Catharanthus roseus Callus
@article{Marfori2002TrichosetinAN,
title={Trichosetin, a Novel Tetramic Acid Antibiotic Produced in Dual Culture of Trichoderma harzianum and Catharanthus roseus Callus},
author={E. C. Marfori and S. Kajiyama and E. Fukusaki and A. Kobayashi},
journal={Zeitschrift f{\"u}r Naturforschung C},
year={2002},
volume={57},
pages={465 - 470}
}The dual culture of Trichoderma harzianum and Catharanthus roseus callus produced an antimicrobial compound with a remarkable activity against the Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis. Structural elucidation revealed that this compound, which we have named trichosetin, is a novel tetramic acid (2,4-pyrrolidinedione) antibiotic and a homolog of the fungal metabolite equisetin. This compound however, was not produced in the individual culture of T. harzianum or C… CONTINUE READING
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