Trichophyton rubrum secreted and membrane-associated carboxypeptidases.

  title={Trichophyton rubrum secreted and membrane-associated carboxypeptidases.},
  author={Christophe Zaugg and Olivier Jousson and Barbara L{\'e}chenne and Peter Staib and Michel Monod},
  journal={International journal of medical microbiology : IJMM},
  volume={298 7-8},
Dermatophytes are the most common agents of superficial mycoses, and exclusively infect stratum corneum, nails or hair. Therefore, secreted proteolytic activity is considered a virulence trait of these fungi. In a medium containing protein as a sole nitrogen and carbon source Trichophyton rubrum secretes a metallocarboxypeptidase (TruMcpA) of the M14 family according to the MEROPS proteolytic enzyme database. TruMcpA is homologous to human pancreatic carboxypeptidase A, and is synthesized as a… CONTINUE READING


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