Trichloroethylene exposure and trichloroethylene metabolites in urine and blood

After trichloroethylene (Tri) inhalation the metabolite trichloroethanol (TCE) is excreted rapidly in the urine, while trichloroacetic acid (TCA) accumulates in the organism due to a high plasma protein binding rate. After exposure of 5 volunteers to 50 ppm Tri for 6 h, 50 μg/ml TCA is found in the plasma at the end of the 5th exposure day, the amount of… CONTINUE READING