Trichinella spiralis infection reduces tumor growth and metastasis of B16-F10 melanoma cells.

@article{Kang2013TrichinellaSI,
  title={Trichinella spiralis infection reduces tumor growth and metastasis of B16-F10 melanoma cells.},
  author={Yun-Jeong Kang and Jin-Ok Jo and Min-Kyoung Cho and H S Yu and Sun-Hee Leem and Kyoung Seob Song and Mee Sun Ock and Hee-Jae Cha},
  journal={Veterinary parasitology},
  year={2013},
  volume={196 1-2},
  pages={106-13}
}
Recently, attempts have been made to use parasites as novel candidates for live vaccine vectors against solid tumors. In this study, we examined the effects of Trichinella spiralis (T. spiralis) infection on solid tumor growth and metastasis. After oral infection with T. spiralis larvae, B16-F10 cells were injected subcutaneously and intravenously into C57BL/6 mice to evaluate tumor growth and metastatic potential, respectively. Tumor growth and lung metastases in T. spiralis infected mice were… CONTINUE READING