Trichiconlides A and B: two novel limonoids from the fruits of Trichilia connaroides.

@article{An2016TrichiconlidesAA,
  title={Trichiconlides A and B: two novel limonoids from the fruits of Trichilia connaroides.},
  author={Fa-liang An and Jun Luo and Xiaobing Wang and Ming-Hua Yang and Lingyi Kong},
  journal={Organic \& biomolecular chemistry},
  year={2016},
  volume={14 4},
  pages={
          1231-5
        }
}
Trichiconlides A (1) and B (2), two novel limonoids, were isolated from the fruits of Trichilia connaroides. Compound 1 is a novel limonoid with a highly rearranged A/B ring system and an intact D ring, which formed an unprecedented 5/6/5/6/5 carbon skeleton. Trichiconlide B (2) possesses a 10-oxatricyclo[3.3.1.(3,8)]decane core and formed a cage-like structure located between rings A and C. Their structures and absolute configurations were elucidated by spectroscopic methods, single crystal X… 
Spirotrichilins A and B: Two Rearranged Spirocyclic Limonoids from Trichilia connaroides.
Spirotrichilins A (1) and B (2), two novel limonoids with an unprecedented spiro[cyclopenta[b]furan-2,1'-cyclopentan] ring system in A/B/C rings, were isolated from the fruits of trichilia
Highly oxygenous trichilin-type limonoids from Trichilia sinensis.
A new insecticidal havanensin-type limonoid from the roots of Trichilia sinensis Bentv.
TLDR
Trisinlin A showed significant insecticidal activity against newly hatched larvae of Spodoptera litura and was unambiguously determined through comprehensive spectroscopic analyses including 1D and 2D NMR, and mass spectrometry.
Walrobsins A and B, Two Anti-inflammatory Limonoids from Root Barks of Walsura robusta.
TLDR
Walrobsins A and B, two limonoids featuring an unprecedented 5-oxatricyclo[5.4.11,4]hendecane ring system, were isolated from the root barks of Walsura robusta and possessed a stable hemiketal structure formed between the OH-11 and 3-carbonyl group in the hexatomic oxoheterocyclic ring.
Phragmalin-type limonoids from the roots of Trichilia sinensis
Twelve new phragmalin-type limonoids, including trichisintons A–D (1–4), which contain an unusual bicyclo[5.2.14,10]decane motif in the tetranortriterpenoid core, and trisinenmalins A–C and E–I (5–7
Limonoids from the genus Trichilia and biological activities: review
TLDR
An evaluation was performed of all naturally occurring limonoids from the Trichilia genus as well as their various bioactivities, finding the compounds with the intact and seco rings are present in greater quantity in the native species of America and Africa, since the rearranged limonoid are concentrated in the Asian species.
...
...

References

SHOWING 1-10 OF 15 REFERENCES
Trichinenlides A-T, mexicanolide-type limonoids from Trichilia sinensis.
TLDR
Twenty new mexicanolide-type limonoids, namely, trichinenlides A-T (1-20), and 11 known analogues were isolated from the leaves and twigs of Trichilia sinensis and exhibited inhibition against lipopolysaccharide-induced nitric oxide production in RAW 264.
Khayseneganins A-H, limonoids from Khaya senegalensis.
TLDR
Eight new limonoid, khayseneganins A-H (1-8), and 31 known limonoids were isolated from the leaves and twigs of Khaya senegalensis and showed antimicrobial activities against Pseudomonas aeruginosa, MRSA 92(#), and MRSA 98(#).
Two limonoids, khayalenoids A and B with an unprecedented 8-oxa-tricyclo[4.3.2.0(2,7)]undecane motif, from Khaya senegalensis.
Two limonoids, namely khayalenoids A (1) and B (2) with an unprecedented 8-oxa-tricyclo[4.3.2.0(2,7)]undecane motif in the nortriterpenoid core, were isolated from the stems of Khaya senegalensis.
Phragmalin- and mexicanolide-type limonoids from the leaves of Trichilia connaroides.
TLDR
Phytochemical investigation of the leaves of Trichilia connaroides afforded 12 new limonoids with phragmalin- and mexicanolide-type skeletons, including the absolute configuration of 3, which showed moderate cytotoxicity against HL-60 cells.
D-ring-opened phragmalin-type limonoid orthoesters from the twigs of Swietenia macrophylla.
TLDR
The (1)H NMR-based conformational analysis on the epimeric compounds 1 and 2 provided a general approach to determine the absolute configuration of the 2,3-epoxy-2-methylbutyryloxy unit at C-3 borne by a large group of the known phragmalin-type limonoid orthoesters.
Bioactive limonoid and triterpenoid constituents of Turraea pubescens.
Eleven new limonoids, turrapubins A-K (1-11), and three new triterpenoids (12-14), along with 14 known compounds, were isolated from the twigs of Turraea pubescens. The structures of 1-14 were
Chemical constituents from Trichilia connaroides and their nitric oxide production and α-glucosidase inhibitory activities.
Phytochemical investigation of the stem and bark of Trichilia connaroides led to the isolation of eight new nortriterpenoids (1-8), along with fifteen known compounds (9-23). Their structures were
Inhibitory effect of four triterpenoids from trichilia connaroides on nitric oxide production in lipopolysaccharide-stimulated RAW264.7 cells.
TLDR
Two new highly rearranged trichiliton-type limonoids and two new cycloartane-type triterpenoids were isolated from the stem and bark of Trichilia connaroides, and inhibitory effect of these compounds on lipopolysaccharide-induced nitric oxide production in mouse macrophage RAW264.7 cells was evaluated.
...
...