Tricarboxylic acid cycle activity in perfused rat lungs after O2 exposure.

Abstract

O2-induced impairment of mitochondrial energy generation was examined in intact lungs isolated from rats after 18-30 h exposure to either air or 100% O2 in vivo. Mitochondrial metabolic rates were determined by separate measurements of 14CO2 production from [1-14C]pyruvate and [U-14C]palmitate, perfused under normal and stimulated metabolic conditions… (More)

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@article{Bassett1992TricarboxylicAC, title={Tricarboxylic acid cycle activity in perfused rat lungs after O2 exposure.}, author={D. J. Bassett and S. S. Reichenbaugh}, journal={The American journal of physiology}, year={1992}, volume={262 4 Pt 1}, pages={L495-501} }