Tributyltin exposure causes decreased granzyme B and perforin levels in human natural killer cells.

@article{Thomas2004TributyltinEC,
  title={Tributyltin exposure causes decreased granzyme B and perforin levels in human natural killer cells.},
  author={Leeshawn D Thomas and Hemangini V Shah and Stephanie A Green and Arthur D. Bankhurst and Margaret M Whalen},
  journal={Toxicology},
  year={2004},
  volume={200 2-3},
  pages={221-33}
}
Natural Killer (NK) cells are a subset of lymphocytes that are capable of killing tumor cells, virally infected cells and antibody coated cells. Tributyltin (TBT) is a toxic chemical used for various industrial purposes such as: slime control in paper mills, disinfection of circulating industrial cooling waters, anti-fouling agents in shower curtains and the preservation of wood. TBT can be found in edible items such as dairy products and fish. This study investigates the mechanism by which TBT… CONTINUE READING