Tributyltin causes abnormal development in embryos of medaka, Oryzias latipes.

@article{Hano2007TributyltinCA,
  title={Tributyltin causes abnormal development in embryos of medaka, Oryzias latipes.},
  author={Takeshi Hano and Yuji Oshima and Sang Gyoon Kim and Hina Satone and Yumi Oba and Takeshi Kitano and Suguru Inoue and Yohei Shimasaki and Tsuneo Honjo},
  journal={Chemosphere},
  year={2007},
  volume={69 6},
  pages={
          927-33
        }
}
We examined the effects of tributyltin (TBT) on embryonic development, hatching success and sexual differentiation in Japanese medaka (Oryzias latipes). Embryos (within 8h after fertilization) were exposed to TBT in ovo via nanoinjection at concentrations of 0 (control), 0.16, 0.80, 3.96, 19.2 and 82.1 ng/egg. Embryonic survival, development and hatching were observed. Hatched fry were reared until 60 days when they sexually matured, and sexual differentiation was also examined by accordance of… CONTINUE READING
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