Tribulosin and beta-sitosterol-D-glucoside, the anthelmintic principles of Tribulus terrestris.

@article{Deepak2002TribulosinAB,
  title={Tribulosin and beta-sitosterol-D-glucoside, the anthelmintic principles of Tribulus terrestris.},
  author={Mundkinajeddu Deepak and G Dipankar and D'souza Prashanth and M K Asha and Agarwal Amit and Bhagyalakshmi Venkataraman},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2002},
  volume={9 8},
  pages={753-6}
}
Successive extracts of Tribulus terrestris prepared using petroleum ether, chloroform, 50% methanol and water were tested for anthelmintic activity in-vitro using the nematode Caenorhabditis elegans. The activity could be detected only in 50% methanol extract which on further bioactivity guided fractionation and chromatographic separation yielded a spirostanol type saponin, tribulosin and beta-sitosterol-D-glucoside. Both the compounds exhibited anthelmintic activity with ED50 of 76.25 and 82… CONTINUE READING