Tribolium Wnts: evidence for a larger repertoire in insects with overlapping expression patterns that suggest multiple redundant functions in embryogenesis

@article{Bolognesi2007TriboliumWE,
  title={Tribolium Wnts: evidence for a larger repertoire in insects with overlapping expression patterns that suggest multiple redundant functions in embryogenesis},
  author={Renata Bolognesi and Anke Beermann and Laila Farzana and Nadine Wittkopp and Rebekka Lutz and Guillaume Balavoine and Susan J. Brown and Reinhard Schr{\"o}der},
  journal={Development Genes and Evolution},
  year={2007},
  volume={218},
  pages={193-202}
}
wingless (wg)/Wnt family genes encode secreted glycoproteins that function as signalling molecules in the development of vertebrates as well as invertebrates. In a survey of Wnt family genes in the newly sequenced Tribolium genome, we found a total of nine Wnt genes. In addition to wg or Wnt1, Tribolium contains orthologs of the vertebrate Wnt5–7 and Wnt9–11 genes. As in Drosophila, Wnt1, Wnt6 and Wnt10 are clustered in the genome. Comparative genomics indicates that Wnt9 is also a conserved… CONTINUE READING

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Evolution of the Insects

  • D Grimaldi, MS Engel
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