Tribendimidine: a promising, safe and broad-spectrum anthelmintic agent from China.

  title={Tribendimidine: a promising, safe and broad-spectrum anthelmintic agent from China.},
  author={Shu-hua Xiao and Wu Hui-Ming and Marcel Tanner and J{\"u}rg Utzinger and Wang Chong},
  journal={Acta tropica},
  volume={94 1},
We review, for the first time, a 20-year Chinese story of research and development pertaining to tribendimidine, a promising anthelmintic agent that is safe and exhibits a broad spectrum of activity. Tribendimidine was first synthesized at the National Institute of Parasitic Diseases in Shanghai in the mid 1980s. In laboratory studies, tribendimidine showed high efficacy against Nippostrongylus braziliensis in rats, Necator americanus in hamsters, Ancylostoma caninum and Toxocara canis in dogs… CONTINUE READING


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