Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response

@inproceedings{Wennemers2011TribblesH3,
  title={Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response},
  author={Marloes Wennemers and Johan Bussink and Blanca Scheijen and Iris Nagtegaal and Hanneke W M van Laarhoven and James A. Raleigh and Mahesh A. Varia and Joop J T M Heuvel and Kasper M A Rouschop and Fred C. G. J. Sweep and Paul N Span},
  booktitle={Breast Cancer Research},
  year={2011}
}
Hypoxia in solid tumors is associated with treatment resistance, resulting in poor prognosis. Tribbles homolog 3 (TRIB3) is induced during hypoxia and is involved in multiple cellular pathways involved in cell survival. Here, we investigated the role of TRIB3 in breast cancer. TRIB3 mRNA expression was measured in breast tumor tissue from 247 patients and correlated with clinicopathological parameters and clinical outcome. Furthermore, we studied TRIB3 expression regulation in cell lines… CONTINUE READING
27 Citations
51 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 51 references

Similar Papers

Loading similar papers…