Trib3 is regulated by IL-3 and affects bone marrow-derived mast cell survival and function.

Abstract

Mast cells are the principal effectors of IgE-mediated immune responses, including allergic reactions. Tribbles homolog 3 (Trib3) encodes a pseudokinase implicated in the cellular stress response and has been linked to inflammation in certain situations. Here we report the role of Trib3 in mouse bone marrow-derived mast cells (BMMCs). Our results show that… (More)
DOI: 10.1016/j.cellimm.2012.11.011

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Cite this paper

@article{Ord2012Trib3IR, title={Trib3 is regulated by IL-3 and affects bone marrow-derived mast cell survival and function.}, author={Tiit Ord and Daima Ord and Sulev Kuuse and Mario Plaas and T{\~o}nis Ord}, journal={Cellular immunology}, year={2012}, volume={280 1}, pages={68-75} }