Triamterene and renal stone formation.

  title={Triamterene and renal stone formation.},
  author={Donald B. White and George H. Nancollas},
  journal={The Journal of urology},
  volume={127 3},
We investigated the influence of triamterene (TA), and its metabolites parahydroxytriamterene (PHTA), and parahydroxytriamterene sulfate (PHTAS) on the nucleation and crystal growth of calcium oxalate monohydrate (COM), in supersaturated solution at 37C using a new constant composition technique. The spontaneous precipitation of COM is preceded by induction periods which decrease with increasing supersaturation. The addition of the triamterene seed materials substantially reduces there delay… CONTINUE READING

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