Trials in isolated systolic hypertension: an update.

  title={Trials in isolated systolic hypertension: an update.},
  author={Bernard Waeber},
  journal={Current hypertension reports},
  volume={5 4},
Isolated systolic hypertension (ISH) has proved to be a powerful predisposing factor for cardiovascular diseases in the elderly. Recent placebo-controlled interventional trials such as the Systolic Hypertension in the Elderly Program (SHEP), the Systolic Hypertension in Europe (Syst-Eur), and the Systolic Hypertension in China (Syst-China) showed that the lowering of systolic blood pressure using a diuretic- or a calcium antagonist-based treatment is associated with a decrease in cardiovascular… CONTINUE READING