Trial of vitamin D supplementation to prevent asthma exacerbation in children

@article{Krishnan2017TrialOV,
  title={Trial of vitamin D supplementation to prevent asthma exacerbation in children},
  author={Elango Krishnan and Venmugil Ponnusamy and S Sekar},
  journal={International Journal of Research in Medical Sciences},
  year={2017},
  volume={5},
  pages={2734-2740}
}
Background: To assess the level of vitamin D in children with bronchial asthma and to study the effects of vitamin D supplementation in asthmatic children who had vitamin D deficiency in terms of asthma control test score and Number of exacerbations. Methods: This interventional study was conducted in Department of Paediatrics, KAPV Government medical college, Trichy, Tamil Nadu, India from September 2016 to February 2017. 96 asthmatic children of age group 5-12 years who attended outpatient… 

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References

SHOWING 1-10 OF 14 REFERENCES
Vitamin D Deficiency as a Strong Predictor of Asthma in Children
TLDR
It was revealed that the majority of asthmatic children had vitamin D deficiency compared to control children, and Vitamin D deficiency was the major predictor of asthma in Qatari children.
Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study.
Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren.
TLDR
It is suggested that vitamin D(3) supplementation during the winter may reduce the incidence of influenza A, especially in specific subgroups of schoolchildren.
Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma.
TLDR
Lower vitamin D levels in children with STRA were associated with increased ASM mass and worse asthma control and lung function, and the link between vitamin D, airway structure, and function suggests vitamin D supplementation may be useful in pediatric STRA.
Vitamin D deficiency in childhood — A review of current guidelines on diagnosis and management
TLDR
Routine supplementation starting from newborn period is being increasingly endorsed by various international organizations and consists of vitamin D supplementation as Stoss therapy or daily or weekly oral regimens with equal efficacy and safety, combined with calcium supplements.
Risk factors for development of bronchial asthma in children in Delhi.
Prevalence of Bronchial Asthma in Indian Children
  • R. Pal, S. Dahal, Shrayan Pal
  • Medicine
    Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
  • 2009
TLDR
The findings indicate that the burden of bronchial asthma in Indian children is higher than was previously understood.
Serum Vitamin D Levels and Markers of Severity of Childhood Asthma in Costa Rica
TLDR
To determine whether vitamin D levels are associated with asthma severity and allergy during childhood, six hundred sixteen Costa Rican children with asthma, 6 to 14 years of age, were included.
Prevalence of bronchial asthma in schoolchildren in Delhi.
TLDR
The prevalence of bronchial asthma and wheezing in children in Delhi is quite high and comparable to that reported from several developed countries, and a positive family history of asthma and presence of smokers in the family emerged as significant risk factors.
Prevalence and severity of asthma, rhinitis, and eczema in Singapore schoolchildren.
TLDR
Demographic and socioeconomic factors appear to influence the prevalence and severity of asthma and allergic diseases in Singapore schoolchildren.
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