Trial of amitriptyline for relief of pain in amputees: results of a randomized controlled study.

@article{Robinson2004TrialOA,
  title={Trial of amitriptyline for relief of pain in amputees: results of a randomized controlled study.},
  author={Lawrence R. Robinson and Joseph M. Czerniecki and Dawn Marie Ehde and William Thomas Edwards and David A Judish and Myron L Goldberg and Kellye M Campbell and Douglas G. Smith and Mark P Jensen},
  journal={Archives of physical medicine and rehabilitation},
  year={2004},
  volume={85 1},
  pages={1-6}
}
OBJECTIVE To evaluate whether amitriptyline is more effective than placebo in improving phantom limb pain or residual limb pain. DESIGN Randomized controlled trial of amitriptyline for 6 weeks. SETTING University hospital. PARTICIPANTS Thirty-nine persons with amputation-related pain lasting more than 6 months. INTERVENTION Six-week trial of amitriptyline (titrated up to 125 mg/d) or an active placebo (benztropine mesylate). MAIN OUTCOME MEASURES Analyses were conducted to examine… CONTINUE READING

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