• Corpus ID: 29482541

Trial of Momordica charantia Linn (Karela) powder in patients with maturity-onset diabetes.

  title={Trial of Momordica charantia Linn (Karela) powder in patients with maturity-onset diabetes.},
  author={M. S. Akhtar},
  journal={JPMA. The Journal of the Pakistan Medical Association},
  volume={32 4},
  • M. Akhtar
  • Published 1982
  • Medicine
  • JPMA. The Journal of the Pakistan Medical Association
Powdered whole Aloviordica charantia fruit (bitter gourd) was tried on eight patients suffering from uncomplicated maturity-onset diabetes. The patients were told to take the, powdered drug in milk twice daily at the rate of 50 mg/kg body weight, to continue on the carbohydrate deficient diet as before, and not to take any other medication. The results obtained show that the drug produced a consistent hypoglycaeinic effect in all the patients. The mean blood sugar levels after drug treatment at… 
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The present article reviews the clinical data regarding the anti-diabetic potentials of M. charantia and calls for better-designed clinical trials to further elucidate its possible therapeutic effects.
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  • M. Akhtar, M. Ali
  • Medicine, Biology
    JPMA. The Journal of the Pakistan Medical Association
  • 1984
The treated rabbits did not show any signs of acute toxicity which encourages the possible use of this compound medicinal plant prescription by diabetic patients, and it is conceivable that this folk medicine contains some hypoglycaemic principles which can reduce the blood glucose levels of diabetics.
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  • Medicine
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  • 1992
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From the results, it could be concluded that MOMORDICA CHARANTIA fruit possessed a significant and consistent hypoglycaemic effect in normal and alloxandiabetic rabbits.
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Clinical study of an insulin-like compound obtained from vegetable source (vegetable insulin) showed a consistent hypoglycaemic effect in patients with diabetes mellitus and the average fall in blood sugar level at the peak effect of vegetable insulin was found to be statistically significant.
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