Trial of Daily Vitamin D Supplementation in Preterm Infants

  title={Trial of Daily Vitamin D Supplementation in Preterm Infants},
  author={Chandra Kumar Natarajan and Mari Jeeva Sankar and Ramesh Agarwal and Oleti Tejo Pratap and Vandana Jain and Nandita Gupta and Arun Gupta and Ashok Deorari and Vinod Kumar Paul and Vishnubhatla Sreenivas},
  pages={e628 - e634}
OBJECTIVE: To compare the effect of 800 vs 400 IU of daily oral vitamin D3 on the prevalence of vitamin D deficiency (VDD) at 40 weeks’ postmenstrual age (PMA) in preterm infants of 28 to 34 weeks’ gestation. METHODS: In this randomized double-blind trial, we allocated eligible infants to receive either 800 or 400 IU of vitamin D3 per day (n = 48 in both groups). Primary outcome was VDD (serum 25-hydroxyvitamin D levels <20 ng/mL) at 40 weeks’ PMA. Secondary outcomes were VDD, bone mineral… 

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