Tretinoin Nanogel 0.025% Versus Conventional Gel 0.025% in Patients with Acne Vulgaris: A Randomized, Active Controlled, Multicentre, Parallel Group, Phase IV Clinical Trial.

@article{Chandrashekhar2015TretinoinN0,
  title={Tretinoin Nanogel 0.025% Versus Conventional Gel 0.025% in Patients with Acne Vulgaris: A Randomized, Active Controlled, Multicentre, Parallel Group, Phase IV Clinical Trial.},
  author={B. S. Chandrashekhar and Ms. S. Anitha and Mukesh Ruparelia and Pradyumna Vaidya and Riyaz Aamir and S. K. Shah and Santharam Thilak and Sanjeev Jayanth Aurangabadkar and Sandeep Pal and Abir Saraswat and Jayesh Sanmukhani},
  journal={Journal of clinical and diagnostic research : JCDR},
  year={2015},
  volume={9 1},
  pages={
          WC04-9
        }
}
BACKGROUND Conventional topical tretinoin formulation is often associated with local adverse events. Nanogel formulation of tretinoin has good physical stability and enables good penetration of tretinoin into the pilo-sebaceous glands. AIM The present study was conducted to assess the efficacy and safety of a nanogel formulation of tretinoin as compared to its conventional gel formulation in the treatment of acne vulgaris of the face. MATERIALS AND METHODS This randomized, active controlled… CONTINUE READING

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