Treponemycin, a nitrile antibiotic active against Treponema hyodysenteriae.

@article{Singh1985TreponemycinAN,
  title={Treponemycin, a nitrile antibiotic active against Treponema hyodysenteriae.},
  author={S. Singh and S. Gurusiddaiah and J. W. Whalen},
  journal={Antimicrobial Agents and Chemotherapy},
  year={1985},
  volume={27},
  pages={239 - 245}
}
Two strains of Streptomyces sp. (isolates 275 and 124) were isolated from soil samples collected from the fields around Lewiston, Idaho. Based on their cellular morphology and physiology, the two isolates were identified as Streptomyces albovinaceous. Both isolates produced an antibiotic when grown in liquid culture medium containing homogenized oats. The antibiotic (treponemycin) was isolated from the culture broth by solvent extraction and purified by silica gel column and preparative thin… Expand
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