Treponema denticola TroR is a manganese- and iron-dependent transcriptional repressor

@article{Brett2008TreponemaDT,
  title={Treponema denticola TroR is a manganese- and iron-dependent transcriptional repressor},
  author={Paul J. Brett and Mary N. Burtnick and J Christopher Fenno and Frank C Gherardini},
  journal={Molecular Microbiology},
  year={2008},
  volume={70},
  pages={396 - 409}
}
Treponema denticola harbours a genetic locus with significant homology to most of the previously characterized Treponema pallidum tro operon. Within this locus are five genes (troABCDR) encoding for the components of an ATP-binding cassette cation-transport system (troABCD) and a DtxR-like transcriptional regulator (troR). In addition, a sigma(70)-like promoter and an 18 bp region of dyad symmetry were identified upstream of the troA start codon. This putative operator sequence demonstrated… CONTINUE READING

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